Forskolin: The Weight Loss Trend Continues
For many years, forskolin has been basking in the accolade of being the world’s premium miracle supplement.
What many people do not know is that, since ancient times, forskolin has been used by traditional medicine practitioners and ethnoherbologists to treat a variety of health conditions. This can only suggest that forskolin may have more beneficial effects than being a mere weight-loss supplement.
Celebrity physician, Dr. Oz, was once quoted saying forskolin may perhaps be the best “lightening in a bottle” giving credence to the belief of many that the product can indeed do wonders in their goal of shedding excess pounds. Scientists believe however, that forskolin may hold to key to the management of other more serious health problems.
As chemical specialists who want to know the finer details of dosing with coleus forskohlii root, we will be examining all of the information available and giving a run down if we think you should be worried about the potential forskolin extract side effects. Others who have pointed it out before us are clearly concerned and caution going over board by assuming this is a miracle labdane diterpenoid ingredient and nothing could ever go wrong or throw something out of whack.
Coleus Forskohlii Fact or Myth?
For centuries, man has been using forskolin to manage the various symptoms they associate with certain diseases as well as other illness states. We have listed below some of these supposed forskolin benefits which are, in themselves, nothing less than truly remarkable if you take all at face value. It gives the impression that forskolin may well be a wonder health supplement because it provides individuals one basic solution to many health problems which would have otherwise been solved with multi-drug therapy in modern medical practice.
The question us scientific-minded individuals want to know is how effective and efficient coleonol is not only dealing with the fat issue, but also skin, energy and musclar functionality surrounding the forskolin data presently circulating the internet.
Consider forskolin as an all-in-one health solution for many health problems such as, but not limited to, the following:
- Certain heart conditions – supposedly effective in improving heart muscle contraction
- Asthma – forskolin is said to alleviate the symptoms of asthma
- Obesity – a great weight-loss supplement to aid in shedding excess weight
- Cancer- forskolin has been regarded as effective in preventing colon cancer
- Glaucoma – forskolin has been shown to reduce the pressure inside the eyes
- Neuromuscular condtions – forskolin is shown as a possible treatment for Parkinson’s disease
- Infections – it has a palliative effect in reducing urinary tract infections
- Skin diseases – forskolin may provide some degree of protection for the skin
- Hearing loss – forskolin may possibly be beneficial to recovery after hearing loss
The list is just an amalgamation of anecdotal evidence and some degree of scientific investigation in a few of these supposed benefits. While much work needs to be done, especially in the conduct of experimental, case-controlled clinical studies establishing once and for all the effectiveness and safety profile of forskolin, healthcare consumers must be made aware of the evidence-based benefits of forskolin on their health and wellbeing to weed out hearsay from real scientific evidence.
A Real Evidence-Based Forskolin Guide?
Given the centuries-old use of forskolin in the management of a variety of diseases that has plagued man, from heart conditions to asthma and even neuromuscular diseases such as Parkinson’s, albeit in a folkloric type of traditional medicine, it really does leave an impression of its many health benefits.
Throughout this article, we will slowly introduce you to the world of forskolin. We shall look at the hype that is now creating frenzy in the world of increasing awareness on the need to lead healthier and more meaningful lives. We shall also take a look at some of forskolin’s well-documented and duly recognized health benefits that are slowly being integrated by members of the medical community in their treatment regimen.
As you may already know, not everything that you read on the internet is based on solid science. By looking at the results of clinical studies on the effectiveness, efficacy, and safety profile of forskolin, we may at last shed some light into the myth-or-fact dilemma that has bannered many of these so-called internet health wonders. We believe that by giving you the correct information, backed by scientific evidence, you will be able to safely navigate through the maze of nutritional supplementation and alternative medicine especially those on the net.
Talking about Trends
Google Trends show a dramatic increase in consumer interest for forskolin. The sudden surge in health consumer interest has been closely associated with the remarks given by Dr.Oz in one of the TV show’s episodes purportedly elevating forskolin to a status never before heard of in the western hemisphere. Consumers were quick to respond by searching for any information they can about the uses and benefits of forskolin especially on weight loss. This is perhaps one of the major reasons why forskolin showed a dramatic increase in Google searches among those living in the United States as well as Australia, Hungary, Canada and Poland.
With the ever-increasing number of Americans getting obese every single day. It is understandable that many of the internet searches are related to products and services that provide weight loss.
The health consumerism is undeniably robust in the United States. With most health products in the internet geared primarily for American consumers, it is no wonder that the bulk of Google searches originate from the country as well. However, having Hungary and Poland, both Eastern European countries with a storied past, on the list may make one wonder how could that be possible.
The only plausible explanation is exposure to aggressive online media campaign coupled with reference to Dr. Oz’s remarks on the weigh-loss effectiveness of forskolin. In fact, there is not a single forskolin product consumer and user review on Amazon that does not mention Dr. Oz as one of the reasons for their decision to purchase forskolin. Such is the unparalleled trust given by today’s consumers to celebrities that everything they say is deemed true. Unfortunately, this blind faith in the competence of another may prove to be disastrous in some cases.
It is no secret that Dr. Oz, like other celebrity physicians, is at odds with the US Food and Drug Administration especially for the claims that he makes on his TV show. Many in the scientific community believe that some assertions made by celebrity physicians are simply not true and most are often baseless. It is firmly believed that the claims are not really reflective of a professional doctor’s rational thinking but is largely motivated by consumer gains and financial rewards.
This is all the more reason why a no-nonsense, evidence-based guide to forskolin must be developed and presented for all to see.
What is Forskolin?
Drugs.com has cited the multi-site action of forskolin giving it the benefit of acting on different parts of the body. Translated into treatment, forskolin is thus pegged as an all-in-one product that can address a variety of health problems and not just weight loss.
Forskolin raises the levels of cyclic adenosine monophosphate or cAMP which is an important substance in mediating biological responses of the different cells of the body to the variety of hormones as well as other extracellular substances. Without cAMP, this communication activity between cells and the other all-important hormones and substances outside the cell will cease to exist. Without extracellular communication, many of life’s processes will eventually cease to function.
Origins and Utilization
Forskolin comes from the roots of a perennial herb that is native to tropical and subtropical regions, more commonly in East Africa and India. It has been used in traditional and ethnoherbal medicine, especially Ayurveda, as treatment for a variety of health conditions. Although Ayurvedic medicine is not necessarily accepted by the medical and scientific community, this kind of traditional and folkloric medicine is not without merit because many people, especially those living in these regions, still do practice them.
Among the conditions supposedly treated by forskolin in the ancient times include digestive problems, skin disorders, infections, and joint and muscle problems. It has also been used as an oral contraceptive as well as for the management of ringworms and syphilis. Whether or not these assertions are true, it was only in the 1970s when forskolin was first formally investigated for its supposed use in cardiovascular activities.
Forskolin and Weight Loss
One of the most common benefits associated with forskolin is weight loss. The Godard study on the effects of forskolin consumption on the body composition of obese and overweight men as well as their hormonal adaptations showed increases in lean body mass as well as a reduction in body fat. Study subjects also showed increased testosterone levels giving credence to the fat-burning qualities of the forskolin compound.
Because the study only included obese men as subjects, many in the world of weight loss treatment wonder if it is also possible to use forskolin to increase the muscle mass of already-thin individuals. It is thus a lot safer to say that forskolin is an effective weight loss regimen for obese individuals or overweight men and women but should not be used to increase lean muscle mass in individuals who are already considered ‘fit’. More scientific studies are needed to ascertain the value of forskolin on lean and thin individuals. This should be an interesting field for future clinical investigations.
Forskolin and Urinary Tract Infections
Since forskolin primarily acts to raise the levels of cyclic AMP in the body, it has been postulated that this second messenger function may be useful in mediating the cellular removal of certain microorganisms that heave been rendered harmless by the body’s immune defenses. This has been the observations noted by several scientists working on the effects of forskolin on Escherichia coli-infected bladders of mice.
Normally, any foreign body that is present inside the normal body environment is effectively rid of by the body’s defenses. Some of these foreign molecules attach to carrier receptors or vesicles that literally engulf them in a tight sac. This is to contain the harmful effects of that foreign material inside the sac. In a process known as exocytosis, these foreign matter-filled sacs are transported out from the cell where it will be destroyed by other cells of the immune system.
When forskolin is introduced into the mice’s system, the spike in cyclic AMP induces an increased communication between the cell and the receptor-based exocytotic sac that contains the E. coli. This stimulates the vesicle to be released into the bloodstream where antibiotics, in combination with the body’s immune defenses, can exert their mechanism of action. The study on mice showed an 80% reduction in the levels of circulating E. coli after forskolin introduction as an adjunct to antibiotic therapy.
This means that forskolin can improve the efficiency and efficacy of antibiotics in the management of urinary tract infections especially those coming from the urinary bladder. Scientists are hopeful that the same mechanism will also be useful in other types of infections.
Forskolin and Hearing Loss
The University of Virginia in Charlottesville has conducted a study on the effects of forskolin on auditory hair cell regeneration in mammals. It is believed that cellular regeneration may be possible if the epithelial cells that line the auditory receptor required for hearing are mediated by the action of cyclic AMP or that the signal pathway is dependent on cyclic AMP. As there are many sensory pathways, forskolin may hold promise in the recognition that it can affect cyclic AMP-dependent systems of sensory-perception.
In the study, forskolin was observed to be particularly useful in the S-phase of cellular division, thereby enhancing the regeneration of these individual acoustic hair cells. More cyclic AMP translates to faster regeneration and thus, the possibility of averting total hearing loss while managing the temporary decrease in auditory acuity.
With all of these benefits, you can already see and experience the influx of pure forskolin supplements invading the marketplace. There is definitely some research and due diligence required in order for you to find the right product and overall coleus forskohlii formula good enough for you.
The ‘Pure Forskolin Extract’ Conclusion
Among these three scientifically-documented effects of forskolin – improvement in lean muscle mass, more efficient removal of E coli from the urinary bladder, and greater chances of auditory hair cell regeneration – one thing definitely stand out: all of these changes show an increase in the levels of cyclic AMP.
The impetus therefore for the scientific community is in the possibility of managing the many beneficial effects of cyclic AMP such that it can be used to target specific parts of the body to elicit a desired outcome. As forskolin has been proven to increase cyclic AMP, the relationship between forskolin and the many action of cyclic AMP should be enough grounds to truly solidify the status of forskolin as a premium miracle supplement.